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KMID : 0882420110800040408
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Korean Journal of Medicine
2011 Volume.80 No. 4 p.408 ~ p.418
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Outcome of Cadaveric Kidney Transplantation from Expanded Criteria Donors
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Park Ja-Yong
Cho Jang-Hee
Yoon Young-Deuk
Song Eun-Joo
Jin Mi-Kyung
Yu Chung-Hoon
Jung Hee-Yeon
Lim Jeong-Hoon
Shin Yong-Bong
Choi Ji-Young
Yoon Se-Hee
Park Sun-Hee
Kim Chan-Duck
Kim Yong-Lim
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Abstract
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Background/Aims : The Korean Network for Organ Sharing (KONOS) was established in 2000, and the KONOS criteria for expanded-criteria donors (ECD) have since been applied to kidney allocation from deceased donors. The outcome of cadaveric kidney transplantation from ECD according to KONOS criteria has not been investigated.
Methods: Seventy-seven cadaveric kidney transplants from January 2003 to December 2009 were recruited retrospectively. Factors that influence the glomerular filtration rate (GFR) of graft kidneys up to 36 months after transplantation were evaluated. Postoperative renal function and allograft and patient survival in the ECD group (n = 28) were compared with those in the standard-criteria donor (SCD) group (n = 49).
Results: The GFR of graft kidneys was different according to donor GFR, age, hypertension history, and cause of brain death. In the ECD group, GFR was lower than that in the SCD group by KONOS criteria. No differences in allograft or patient survival were observed until 3 years after kidney transplantation.
Conclusions: Cadaveric kidney transplantation using the ECD by KONOS criteria is acceptable in term of graft and 3-year patient survival, although the GFR was lower in the ECD than in the SCD group.
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KEYWORD
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Kidney transplantation, Cadaver, Graft survival
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